It is the 23rd century, the entire planet has been ravaged by a nuclear war leaving the world as a nuclear holocaust. The survivors live within a domed city sealed off from the outside world, where the citizens live in a society where everyday is nothing but pleasure. But there is one catch, due to population control and limited resources, all citizens can live until they 30 years old. They have a choice, they can either take part in a extermination ceremony called "Carousel" where they are promised of being reborn or they can go-on-the run and escape outside the city, where they believe a mysterious place called "Sanctuary" exists, and risk being hunted by a elite police force "Sandmen" whose job is to terminate all runners seeking Sanctuary and refuse to die at 30. Logan, a sandman begins to question the system, and meets a woman named Jessica, who believes Logan's doubts about society and Carousel and knows about Sanctuary. Logan and Jessica leaves the city and escapes from the city, where they are joined by a android named Rem, who teaches them about the world they've entered, as Logan and Jessica travels through the apocalyptic United States in search of Sanctuary, as they are pursued by Logan's former partner, Francis, who has been assigned by the council (A group of old men who runs the city) not only to apprehend Logan, but to destroy Sanctuary, and the council will make him a member, if he succeeds.